Trade card depicts a woman dressed as a nun with complete habit gazing toward the upper right corner which contains a crescent moon with the letters AK in the center of the circular ring. Verso of the card features an advertisement for Antikamnia, a medicine used for pain relief.

The Antikamnia Chemical Company was established in St Louis in 1890. Their main products were "antikamnia" medicines, which were a derivative of acetanilid, an anti-fever and pain medication. The medication was sold on its own, or was combined with codeine or quinine to enhance the effects. The company suffered a major setback after the Pure Food and Drug Act was passed in 1906. In 1914, the government prosecuted the company for failing to disclose the source of the active ingredient on their packaging.