David Bryant begins the interview with a discussion of his childhood. Bryant grew up in North Carolina as one of seven children. He began working at age ten, and held various jobs until he earned a scholarship to Wake Forest University. Influenced by his high school science teacher, Bryant double-majored in chemistry and math. While at Wake Forest, he became a lab assistant, and conducted some synthetic research. After receiving his BS in 1958, Bryant decided to attend graduate school at Duke University. Focusing on organic chemistry, he worked on the conversion of organic compounds into dianions under Charlie Hauser. Bryant earned his PhD in 1961 and immediately took a job with Union Carbide Corporation. He worked on developing a method of producing vinyl acetate without halide, and later worked with benzyl acetate, acrylic acid, and rhodium triphenylphosphite in the Oxo process. In the 1970s, Bryant became involved in the scientific side of intellectual property disputes for Union Carbide. Bryant concludes the interview with comments on the nature of industrial research and development, the difficulties of government regulation, and his approaching retirement in 2000.