In this interview Sidney Edelstein begins with his family life in Chattanooga, Tennessee, and includes his early education and experiences at the Baylor School in Chattanooga. He describes his undergraduate career at MIT, his interest in cellulose chemistry, and recalls his first employment at the Dixie Mercerizing Company in the midst of the Depression. The interview continues with Edelstein's early entrepreneurial activities, and his term as an AATCC Research Associate. The formation of Lamede, Inc., and Edelstein's position as research director at Hart Chemical Company are discussed in detail. Edelstein continues with his work with the Army Quartermaster Corps during World War II, and difficulties with the Sylvania Industrial Company. The second section of the interview begins with the formation of the Dexter Chemical Corporation, and continues with the company's development, first products, sales figures, subsidiaries, and international operations. Edelstein explains his interest in the history of dyestuffs, including the articles he wrote, and the benefit of history to the textile industry. The interview continues with Edelstein's key role in the history of the American Chemical Society Division of the History of Chemistry, and focuses on the personalities and operations in the early days of the Division. The origin of the Dexter Award is described, and the first recipients discussed. The interview concludes with Edelstein's philanthropic activities, and the Edelstein Center at the Hebrew University.