This brief, informal interview begins with Taube describing his early career at Cornell University and the University of California, Berkeley, and his decision to accept a position at the University of Chicago, where In 1956 he became chairman of the chemistry department. Taube then discusses his relationship with Warren Johnson, the dean of the physical sciences, who he felt helped the department survive in terms of balancing the budget and finding financial support. Taube then reflects on the history of the chemistry department and the various members of the faculty who ran the department in its early years. Next, Taube discusses his means of funding his research during his early years at the University of Chicago and his work with mass spectrometry. While at the University of Chicago, Taube worked with Frank H. Westheimer amd Willard H. Libby. Taube concludes his interview by discussing the ways in which his career as an instructor at Cornell and the research he was involved with negatively affected his first marriage and how he learned later to delegate authority and find balance between his professional and personal life.